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Sesamin

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Heart Health
Blood Glucose & Weight Management

Common Names: Sesamum indicum

Scientific Names: Sesamum indicum, (7α,7′α,8α,8′α)-3,4:3′,4′-Bis[methylenebis(oxy)]-7,9′:7′,9-diepoxylignane, 5,5′-[(1S,3aR,4S,6aR)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis(2H-1,3-benzodioxole)

Summary

Sesamin, a lignan derived from sesame seeds and oil, has garnered interest for its potential health benefits, particularly in modifying fatty acid metabolism and Vitamin E metabolism. It inhibits specific enzymes, leading to changes in fatty acid levels and increased Vitamin E compounds in the body. Research suggests sesamin's benefits in cardiovascular health, including managing hypertension, atherosclerosis, thrombosis, diabetes, and obesity, primarily through its antioxidant and anti-inflammatory effects. However, while some studies indicate its effectiveness in reducing cholesterol and blood pressure, more extensive human research is required to fully understand sesamin's efficacy and safety as a therapeutic agent or supplement. As with any supplement, it is important to consult a healthcare professional before use. 

Dosage Recommendations
The appropriate dosage of Sesamin can vary depending on individual factors, the specific health goals, and the product's concentration. However, a typical recommended dose for Sesamin supplements ranges from 50 to 150 milligrams (mg) taken once or twice daily. It's crucial to follow the manufacturer's instructions on the product label and consult with a healthcare provider before starting any supplementation, as individual needs and tolerances can differ. Additionally, adjusting the dosage may be necessary based on personal health objectives, so professional guidance can help ensure the most effective and safe use of Sesamin for your specific circumstances.
Scientific Papers
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