Common Names: Rutoside, Quercetin-3-O-rutinoside, Sophorin
Scientific Names: 3′,4′,5,7-Tetrahydroxy-3-[α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyloxy]flavone, (42S,43R,44S,45S,46R,72R,73R,74R,75R,76S)-13,14,25,27,43,44,45,73,74,75-Decahydroxy-76-methyl-24H-3,6-dioxa-2(2,3)-[1]benzopyrana-4(2,6),7(2)-bis(oxana)-1(1)-benzenaheptaphane-24-one
Rutin, also known as rutoside, quercetin-3-O-rutinoside, or sophorin, is a flavonol glycoside combining the flavonol quercetin with the disaccharide rutinose. It's found in various plants, including citrus, passion flower, buckwheat, tea, and apple. While rutin has shown potential in preliminary clinical research for reducing conditions like post-thrombotic syndrome and venous insufficiency, there's no high-quality evidence yet confirming its effectiveness and safety for these uses. Its bioavailability is low due to poor absorption, high metabolism, and rapid excretion, limiting its therapeutic potential. While generally safe, further studies are needed to establish a robust safety profile for human therapeutic benefits.