Ornithine

Ornithine, a nonprotein amino acid integral to the urea cycle, plays a crucial role in ammonia detoxification and energy metabolism. As part of the urea cycle, ornithine binds with carbamoyl phosphate to produce L-Citrulline, releasing urea and thereby reducing ammonia concentrations in the blood. Preliminary evidence suggests ornithine's potential to enhance athletic performance by mitigating elevated ammonia levels, particularly during prolonged cardiovascular exercise. It is involved in the synthesis of polyamines for cell growth and the amino acid proline for collagen production. Additionally, ornithine is sometimes used to promote better sleep and aid in the management of conditions like insomnia and stress. However, while some studies suggest potential benefits, more research is needed to fully understand the extent of its effects and its overall safety. As with any supplement, consulting with a healthcare professional is recommended to determine the appropriate dosage and potential interactions with other medications or health conditions.