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HMB

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Common Names: Hydroxy-MethylButyrate, HMB-FA, beta-hydroxy-beta-methylbutyrate, HMB-Ca, β-hydroxy β-methylbutyrate, CaHMB, β-Hydroxy β-methylbutyric acid

Scientific Names: 3-hydroxy-3-methylbutanoic acid

Summary

HMB (Hydroxymethylbutyrate) is a metabolite of the essential amino acid leucine, known for its role in preventing muscle protein breakdown and reducing the loss of fat-free mass. While it may help preserve strength and muscle mass in older adults during catabolic states, such as aging or illness, evidence of benefits for athletes is inconclusive. HMB stimulates muscle protein synthesis and shows effectiveness in preventing exercise-associated muscle damage after high-intensity workouts. Derived from leucine, HMB is naturally produced in the body and found in small amounts in grapefruit, alfalfa, and catfish. Widely used as a dietary supplement in the fitness and bodybuilding communities, HMB is believed to promote muscle growth, reduce muscle breakdown, and aid in muscle tissue repair. Athletes and those engaged in resistance training often turn to HMB supplements to enhance workout results and support muscle recovery. While generally considered safe, individuals with specific fitness goals should consult with healthcare professionals for personalized advice on dosage and usage.

Dosage Recommendations
The recommended dosage of HMB (beta-hydroxy-beta-methylbutyrate) supplements typically ranges from 1,000 mg (1 gram) to 3,000 mg (3 grams) per day, although specific dosages can vary depending on the product and individual needs. To determine the correct dosage, it's essential to follow the manufacturer's instructions on the product label. Athletes and individuals engaged in strength training may consider higher dosages at the upper end of this range to potentially optimize its muscle-building and muscle-preserving effects. Consulting with a healthcare or fitness professional is advisable, especially for those considering HMB for specific fitness goals, to ensure safe and effective use and to tailor the dosage to individual needs and objectives.
Scientific Papers
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