Erythropoiesis-Stimulating Agents

Common Names: ESA, Erythropoietin Stimulants, Red Blood Cell Boosters

Summary
Erythropoiesis-stimulating agents (ESAs) are a class of pharmaceutical drugs designed to stimulate the production of red blood cells in the bone marrow. These agents are often used to treat conditions characterized by anemia, a deficiency of red blood cells, and low hemoglobin levels. Anemia can result from various factors, including chronic kidney disease, cancer, certain medications, and some chronic diseases. ESAs work by mimicking the action of erythropoietin, a hormone naturally produced by the kidneys that signals the bone marrow to produce red blood cells. By increasing the production of red blood cells, ESAs can help improve oxygen-carrying capacity, alleviate anemia-related symptoms like fatigue and weakness, and reduce the need for blood transfusions. ESAs are typically administered by injection, often under the supervision of a healthcare provider, and their usage involves careful monitoring to avoid potential side effects and ensure that red blood cell levels return to a safe and healthy range. The use of ESAs is subject to medical prescriptions and is typically reserved for individuals with specific medical conditions causing anemia.